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Ghrelin Receptor (GHS-R1a) Selective Activation Ipamorelin acts as a highly selective agonist of the growth hormone secretagogue receptor (GHS-R1a), mimicking the natural hormone ghrelin without affecting other pituitary hormone secretion: Selective binding to GHS-R1a receptors without stimulating ACTH, cortisol, or prolactin release Rapid onset of growth hormone pulse generation (peak levels within 40-60 minutes) No significant effect on appetite stimulation unlike other ghrelin mimetics Preserved feedback regulation through endogenous growth hormone-releasing inhibitory mechanisms Research indicates that ipamorelin releases growth hormone with potency and efficacy similar to GHRP-6 (EC50 approximately 1.3 nmol/L) but with superior selectivity for growth hormone secretion
Promotes Fat MetabolismConjugated linoleic acid is known for its role in supporting fat metabolism, making it a popular choice for weight management and body composition goals
B12 supports energy metabolism, nerve function, and red blood cell production
They are not the same level of certainty
It mainly works on the surface of the skin and is minimally absorbed into the bloodstream
Origin and history, discovery in human plasma Loren Pickart , an American biochemist, discovered GHK-Cu in 1973 during studies of differences between young and old plasma
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