Sara Jo Nixon, the director of the Center for Addiction Research & Education at the University of Florida, told The New York Times in 2025 that alcohol affects "virtually every organ system in the body." She added, "It particularly impacts older adults, because there's already some decline or impact in those areas." The National Institute on Alcohol Abuse and Alcoholism recommends that those 65 years or older and not currently on any medications consume no more than one alcoholic drink per day on average, and no more than seven per week (via Johns Hopkins Medicine).
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A rice-grain-sized amount is a standard starting point