Hydroxocobalamin: Dosage and administration
The peptide accelerated healing despite the metabolic impairments of diabetes, outperforming becaplermin (an FDA-approved diabetic wound treatment) in several parameters
InChi Code: InChI=1S/C62H98N16O22.C2H4O2/c1-31(2)25-37(55(92)74-50(32(3)4)62(99)100)71-46(81)29-65-51(88)33(5)67-53(90)38(26-48(84)85)73-54(91)39(27-49(86)87)72-52(89)34(6)68-57(94)41-15-10-21-75(41)58(95)35(13-7-8-20-63)70-45(80)30-66-56(93)40-14-9-22-76(40)60(97)43-17-12-24-78(43)61(98)42-16-11-23-77(42)59(96)36(18-19-47(82)83)69-44(79)28-64,1-2(3)4/h31-43,50H,7-30,63-64H2,1-6H3,(H,65,88)(H,66,93)(H,67,90)(H,68,94)(H,69,79)(H,70,80)(H,71,81)(H,72,89)(H,73,91)(H,74,92)(H,82,83)(H,84,85)(H,86,87)(H,99,100),1H3,(H,3,4)/t33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,50-,/m0./s1
Kolovrat et al., 2020) bypassing the occlusion (Duzel et al., 2017
Static and electromagnetic fields differently affect proliferation and cell death through acid enhancement of ROS generation in mesenchymal stem cells
These pharmacokinetic differences inform the trade-offs in onset, convenience, and dosing convenience
