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10.1021/mp400787s 95

Publicly available datasets used in this study are at DepMap ( Extended Data Fig

Recent studies also show that -sitosterol suppresses pro-survival signaling cascadesfor instance, an oxidized -sitosterol derivative significantly downregulated phosphorylated ERK1/2 and NF-B p65 levels, leading to increased ceramide accumulation and apoptosis in breast and liver cancer cells (97)

Interestingly, though, GHK-Cu appears to possess anti-cancer properties