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It reduces peripheral insulin sensitivity by interfering with insulin receptor signaling, promoting hepatic gluconeogenesis, and increasing free fatty acid levels

Overall survival was defined as the time from date of diagnosis to death or last known date of follow-up

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Eur J Pharmacol 824:110 Zhou Q, Chen B, Wang X, Wu L, Yang Y, Cheng X, Sun X (2016) Sulforaphane protects against rotenone-induced neurotoxicity in vivo: involvement of the mTOR, Nrf2, and autophagy pathways

More recently, a meta-analysis study linked GSTT1-1 null polymorphism with an increased risk of coronary heart disease 43