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Energizes Metabolism

These hypothalamic hormones enter the primary capillary plexus of the hypophyseal portal system, a network of blood vessels (shown in red) located in the infundibulum (pituitary stalk)

Saccharopinuria is caused by a mutation in the saccharopine dehydrogenase domain of the AASA synthase gene, characterized by high levels of saccharopine in urine

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10.1073/pnas.0611523104 Summary Keywords thiazides, hyperglycemia, metabolic syndrome, loop diuretics, insulin, overweight, hypertension, diabetes Citation Di Fulvio M, Rathod YD and Khader S (2025) Diuretics: a review of the pharmacology and effects on glucose homeostasis