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These findings offer further insights into the relationship between oxidative damage, GPX4 degradation, and cell death outcomes, which can be context-dependent

Yamate T, Kohri K, Umekawa T, Amasaki N, Amasaki N, Isikawa Y et al (1996) The effect of osteopontin on the adhesion of calcium oxalate crystals to Madin-Darby canine kidney cells

Cell 165 ServiddioG.BellantiF.TamborraR.RolloT.CapitanioN.RomanoA

FDA-approved products come in fixed doses

Antihyperuricemic efficacy of Scopoletin-loaded soluplus micelles in yeast extract/potassium oxonate-induced hyperuricemic mice

[52] have suggested that the thiosemicarbazone-mediated collateral sensitivity is likely due to the presence of external stress that leads to increased reactive oxygen species and internalization of P-gp which actively accumulates copper bound-thiosemicarbazone into lysosomal compartments leading to autophagic cell death