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Approximately 90% of the drug is rapidly inactivated by plasma pseudocholinesterase , while only about 10% reaches the neuromuscular junction (NMJ)

Psychiatry 67 , 10101016 (2010)

5.3 Why interpretation remains difficult Three issues complicate interpretation

Among the distinct tau transgenic mouse models, senescence was a robust and invariant response to tau accumulation that correlated with brain atrophy in mice and human PSP (35)

J Cancer Res

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position specific gap penalties and weight matrix choice