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5, 11 Although mast cells have been implicated in arthritis, the exact mechanism(s) by which they cause damage has not been defined

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The finding of disrupted selenium metabolism in patients suggests a potential feed-forward cycle of pharmacological treatment, oxidative stress, renal damage and impaired selenoprotein expression

Hendren RL, James SJ, Widjaja F, Lawton B, Rosenblatt A, Bent S

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By utilizing an engineered Grx1roGFP2 biosensor optimized for fluorescence intensity and targetability, we systematically quantified E GSH in the nucleus, nucleoli, paraspeckles, Cajal bodies, stress granules, p-bodies, and the cytosol