If you are deficient, the NHS will treat you
This involves giving large doses of B12 injections, possibly every day or week, for a certain time
This can be due to COMT, MTR or MTRR genetic mutations which help the body convert B12 into its active forms for use at the enzymatic and cellular level
It is expected to become a treatment method for patients with primary sclerosing cholangitis [182]
Last reviewed: June 6, 2026 Last updated: June 6, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Minimal Side Effects Peptide therapy is well-tolerated by most people, with very few side effects