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Four weeks of Pycnogenol intake led to a reduction of symptom severity by 20%, whereas it was reduced by 4.5% in placebo subjects

What scientists know so far

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An insight into maternal recognition of pregnancy in mammalian species

This effect was reversed by treatment with 30 mg/kg ASA, but not 15 mg/kg ASA, such that there a significant increase in total distance travelled in the NIC/ASA30 group compared with the NIC and NIC/ASA15 groups for week 5 (Figure 2A)