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Chemical reactivity window determines prodrug efficiency toward glutathione transferase overexpressing cancer cells

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The abundance of intestinibacter bartlettii, Streptococcus spp ., and Bacteroides intestinalis is correlated with an increased risk of immune-related adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs), whereas the abundance of Lachnospiraceae spp ., Ligilactobacillus salivarius and Faecalibacterium prausnitzii is associated with the opposite effect 19

doi: 10.1080/1071576021000006581 35 KirlyL.KnstlerA.FattingerM.HllerK.JuhszC.MllerM.et al

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