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Supplementary information Acknowledgements This work was supported by Chang Gung Memorial Hospital [CMRPG391311, CMRPG3A1131, CMRPG3H0611 and Grants CIRPD1D0071-3

Medication Considerations Dopamine-affecting medications require careful consideration in light of current understanding of reward processing

Andersen JM, Ronning PO, Herning H, Bekken SD, Haugen TB, Witczak O

Find out whether supplements or vitamins like iron, magnesium, vitamin E and others can help for restless leg syndrome (RLS)

Constipation is a common but manageable condition

"Even if I'm not hungry, Ill make myself stop and at least eat a snack it has helped tremendously." - Quiggles1982 Simple foods like apples, yoghurt, oatmeal, or smoothies are common go-to choices when other flavours feel overwhelming