Krause A, Neitz S, Magert HJ, Schulz A, Forssmann WG, Schulz-Knappe P, Adermann K: LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
Consequently, a highly significant reduction in systemic gut inflammation is achieved through this multi-targeted healing cascade
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Other indications include malabsorption disorders (such as Crohn's disease or coeliac disease), following gastric surgery, strict vegan diets without supplementation, and certain medications that interfere with B12 absorption
10.1021/ja908372b