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higher purity (98%+) ensures that the collagen-stimulating ghk-cu peptide effects are not diluted by impurities

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Journal of Thoracic and Cardiovascular Surgery 161(2):448-454, 2021

The glutamate residues are added by an amide linkage to the -carboxylate group of the folate derivative

In the prepared briefing documents for the meeting, FDA experts note that there is a lack of evidence on efficacy and safety to justify manufacturing these peptides by pharmacies, and thus they propose not to include them on the 503A Bulks List

10.1093/nargab/lqaa084