Just like anything, too much of a good thing can cause major problems, and this includes effects on our normal physiology
Sepsis patients exhibit upregulation of inducible nitric oxide synthase (iNOS) (Zrzavy et al., 2019), which catalyzes NOS production from L-arginine, in endothelial cells, astrocytes, and microglia, suggesting a proinflammatory state
Lightweight, fast-absorbing
This Epithalon product fits within that broader catalogue as a niche item intended for informed customers who understand the importance of product verification, responsible handling, and compliance with applicable local regulations
Clinics have also experimented with direct NAD+ IV infusions, although it is unclear whether this method of delivery has superior benefits over oral consumption of precursors
However, taking baths might not be tolerable for some people