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FIGURE 4 3.4 Nitazoxanide reduced apoptosis in rats with MTX-hepatotoxicity MTX significantly induced hepatic apoptosis as demonstrated by increased proapoptotic markers, Bax level, and caspase-3 activity (Figures 5A, D) while reduced antiapoptotic Bcl-2 level (Figure 5B) and increased Bax/Bcl-2 ratio (Figure 5C) compared to CTRL group

Plasma levels drop significantly with age

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10.1503/jpn.100057 J Psychiatry Neurosci

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Palatable food access impacts expression of amylin receptor components in the mesocorticolimbic system