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Role of melatonin in Alzheimer's disease: from preclinical studies to novel melatonin-based therapies

It has been extensively studied for its role in skeletal muscle differentiation and the regulation of glucose metabolism 168 (Fig

A product of lipid peroxidation, 4-hydroxynonenal, has been shown to induce apoptosis in neuroblastoma cells by elevating the levels of p53, p63 and p73 and p63 staining has been used as a marker for prostatic adenocarcinoma where lack of p63 staining indicates malignant prostatic adenocarcinoma [14,18]

Hawkins, J., Idoine, R., Kwon, J., Shao, A., Dunne, E., Hawkins, E., Dawson, K., & Nkrumah-Elie, Y

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Biochem Biophys Res Commun (1995) 206:66773