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PubChem Compound Summary for CID 56841945

The emerging role of Nrf2 in mitochondrial function

Strengthens Immunity: Plays a key role in immune system function and nervous system health

While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood

Although Nrf1 is similar to Nrf2 structurally, Nrf1s activity is not controlled by Keap1 (Wang and Chan, 2006)

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