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Before and Aftercare Guidelines Before Your Appointment: Avoid consuming alcohol and/or caffeine for a minimum of 24 hours before coming in for your treatment

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doi: 10.1113/jphysiol.2010.201343

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Interestingly, after Pycnogenol intake, none of the hormone levels showed significant changes compared to baseline or placebo, suggesting non-hormonal mechanisms of Pycnogenol on climacteric symptoms