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Clinical features include weight loss, dystonia, stunted growth, and epilepsy, with an epilepsy incidence of 33.3%, most commonly presenting as generalized tonicclonic and myoclonic seizures ( SCO2 mutations tend to have earlier-onset symptoms that progress more rapidly, including hypertrophic cardiomyopathy, dystonia, and seizures

But it is best to start taking supplements a few months or more before conception, since it may take a few months to get their full benefits

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[DOI] [PubMed] [Google Scholar] 149.Jaeger D, Schoiswohl G, Hofer P, Schreiber R, Schweiger M, Eichmann TO, et al

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