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(147) investigated the status of mitochondrial function markers and oxidative stress in migraine patients

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Decreased expression of MBP and deficient myelination are found postnatally in both adult HD models and PGC-1 knockout mice, whereas PGC-1 overexpression increases MBP promoter activity

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This transporter exchanges intracellular glutamate for extracellular cystine in a 1:1 ratio 21

After staying for a number of days at the decreased altitude (higher pressure), typically on the third day (Sunday afternoons), the family observed behavioral and symptomatic improvement