Side effects: Very few reports so far, but insufficient long-term human data
International Journal of Pharmaceutics 494 , 471478, (2015)
In inflamed or diabetic wounds, keratinocytes, fibroblasts, and macrophages overexpress CD44, while the excessive accumulation of ROS generates a redox-imbalanced milieu analogous to tumor oxidative stress
barbarum exhibited antioxidative and anti-inflammatory effects, primarily through the modulation of mRNA expression levels, suggesting its potential to positively impact metabolic disorders
Cons: lower per-capsule dose (175 mg) means you need 2-4 capsules daily, higher cost per effective dose than standard capsules, no Setria certification, sustained-release clinical data is less robust than liposomal data
If youre considering advanced natural therapies, peptide nasal spray therapy may be a fitting option