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Low B12 levels can lead to megaloblastic anemia, a condition where red blood cells are abnormally large and unable to transport oxygen efficiently, causing symptoms like fatigue, weakness, and breathlessness

nevertheless, no significant differences between the LT 4 administrated and control groups were found

This leads to the cleavage and translocation of AIF from the mitochondrial intermembrane space to the nucleus, phosphorylation of the histone H2A family member H2AX, mitochondrial release of the death-inducing protein Smac/direct IAP-binding protein with low PI (DIABLO), and inhibition of the anti-apoptotic protein X-linked inhibitor of apoptosis (XIAP)

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doi: 10.1007/s10450-014-9606-z 159 ThommesM.KanekoK.NeimarkA

This testing period covers the most vulnerable phase of embryonic development when cancer-causing substances would be most likely to produce abnormalities