The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm 2 nm
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Many researchers notice nothing definitive during the first two weeks
In this classification, major dysmood disorder (largely overlapping with depression, with melancholia and psychotic features and highly recurrent depression) is defined by a higher ROI and/or pronounced symptoms of depression, anxiety, and physiosomatic manifestations, whereas simple dysmood disorder is characterized by a lower ROI index and a less severe presentation of MDD [10]
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