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238 During the development of NAFL/NASH, FFAs overload the mitochondria, FAO, and electron flux in the electron transport chain (ETC) increasing and disrupting mitochondrial homeostasis, leading to excessive production of ROS due to the lack of upregulation of ETC complex activity, which generates electron leakage and subsequently exacerbates lipid accumulation in hepatocytes

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In this study, we observed no significant differences in heart rate between the L-carnitine and placebo groups under both the "standard" and "experimental" protocols (Fig

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More visible benefits (fat loss, muscle tone) typically appear after 8 to 12 weeks

Accessed 24 May 2024