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Appropriate research applications may include: molecular biology peptide chemistry receptor biology protein signalling research cell culture investigations experimental pharmacology biochemical analysis translational research Laboratory Handling Appropriate laboratory procedures support both researcher safety and experimental reproducibility

As these patients were most likely classified as moderate progressors, the results suggested that 50 mg methylcobalamin injections could be beneficial for patients with ALS in the early stage and with moderate progression rate, the researchers wrote

However, it has not been approved for use in standard medicine by the FDA and other global regulatory authorities due to the absence of sufficient and comprehensive clinical studies confirming its health benefits in humans

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Oral therapy is generally unsuitable for pernicious anaemia or conditions affecting the terminal ileum (where B12 is absorbed), as these patients lack intrinsic factor or have damaged absorption sites