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499 Similarly, Duan et al

The cellular and molecular mechanisms that determine the functional polarity of reactive astrocytes remain incompletely understood and are probably regulated by complex, context-dependent signaling networks 2,3

However, the nuclear glutathione pool resisted depletion by BSO but not with DEM

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Rescue potential of P-PantSAc in HoPan treated mice In order to test the rescue potential of P-PantSAc in vivo in an established mammalian setting, we used HoPan-treated mice as previously described 34