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Oxidative Medicine and Cellular Longevity, 2012 , 324832

Facet-mediated pain typically worsens with extension movements and prolonged standing

Two-way ANOVA results reveal significant differences in the metabolites NAA+NAAG, Cr+PCr, and Glc+Tau between early (1 h) and late (4h) administration of rt-PA

IR also allows easier dose adjustments since physicians can increase or decrease individual doses without changing the whole day's coverage

It recruits mast cells to sites of inflammation through a dose-dependent, Gi protein-phospholipase C signaling pathway

For allergies, its bidirectional nature (it can suppress overactive responses) generally makes it appropriate, but monitoring is important