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For patients discontinuing tirzepatide, blood glucose levels should be monitored closely as the medication's glucose-lowering effects diminish

Figure 4: Changes in body weight in A) lean mice and B) obese mice and changes in food intake in C) lean mice and D) obese mice, across the three different experimental treatment groups

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Weight loss was primarily from fat mass rather than lean mass, and the treatment was generally well-tolerated with no significant adverse effects on glucose metabolism, insulin levels, or IGF-1 levels

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