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At 20 mg/mL (dose of 4 mg) the cytokine release is insignificant (35)

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doi: 10.1111/j.1365-2133.2010.10046.x 69 RiedhammerCWeissertR

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Over 26 weeks, including a dose-escalation period of up to 6 weeks, researchers observed mean percentage weight reductions of 6.0% to 10.8% across the cagrilintide dose groups compared to just 3.0% with placebo