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Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species

An ensemble model averaging the predicted probabilities from these four models achieved an AUC of 0.870, outperforming all individual models and the ABCD2 score (AUC, 0.713)

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Discussion In this work, we demonstrate that the detoxifying functions of choroid plexuses that result from conjugation to GSH can be enhanced by activating the Nrf2 signaling pathway in the early postnatal stage of development