Cytochrome 2E1 (CYP2E1) is the primary enzyme responsible for the conversion of acetaminophen to its toxic metabolite
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Partoazar A, Nasoohi S, Rezayat SM, Gilani K, Mehr SE, Amani A, Rahimi N, Dehpour AR (2017) Nanoliposome containing cyclosporine A reduced neuroinflammation responses and improved neurological activities in cerebral ischemia/reperfusion in rat
1,3,6 Additional cytoprotective properties of EGT include chelating redox-active metal ions to prevent the generation of highly destructive hydroxyl radicals and modulating key inflammatory signaling pathways like nuclear factor-kappa B (NF-B)
Chen YH, Cabanillas M, Sperling J, Xu L, Goswami M, Maniakas A, Williams MD, Lai SY, Busaidy N, Dadu R, Zafereo ME , Wang JR