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It should be noted that Cy5.5-ETX in the blood of mice in the treatment group was not completely cleared after three days, but consistently decreased along with DiR-RNPs (Fig

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Nevertheless, most existing studies lack clinical data on AD thus the need for research directed toward the clinical examination to explore the outcome of nanoparticles as future anti-AD nanocoutured therapy

However, excessive inflammation (as in BD) can disrupt normal hypothalamic glucocorticoid receptor feedback-inhibition on cortisol production, resulting in sustained HPA-axis hyperactivity and further inflammation [139, 140]

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