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Growth factors are universally large proteins that are both metabolically labile and too large to pass the blood- brain barrier (BBB)

Retrieved November 1, 2023, from Shah, A

After uptake by cancer cells, Pt (IV) prodrugs are reduced by intracellular GSH to produce active Pt (II) complexes, leading to the exhaustion of GSH

Cell 33 , 113 (2009)

The expression of genes for a series of antioxidant-related enzymes (-glutamylcysteine synthetase, GSH reductase, glutathione- S -transferase, GSH peroxidase, and superoxide dismutase) in diverse tissues was upregulated by these supplements [35]