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That's huge

Mass production of cigarettes also increased their availability

[1] Smoking is primarily practiced as a route of administration for psychoactive chemicals because the active substances within the burnt, dried plant leaves (or other chemical) can vaporize into a gaseous state and be delivered into the respiratory tract, where they are rapidly absorbed into the bloodstream through the lungs and can reach the central nervous system

However, the biggest obstacle lies in homogenization competition

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