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Use of certain medications that may interact with B12 or choline metabolism (e.g., metformin, proton pump inhibitors, or anticholinergic drugs)

(PubMed) Chrysant SG, Chrysant GS

(b) lack of effective statistical analysis

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Additionally, the concentration of AOD9604 in the synovial fluid after injection was estimated to be about 0.19 mg/mL, similar to concentrations used in previous GH injection studies in animal models