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Cells were extensively washed with PBS, fixed in 4% PFA for 15 min, permeabilized and blocked with 0.01% saponin/10% normal goat/PBS serum and stained with the primary antibodies in the same blocking solution in a humid chamber

Amp Psychiatry 105 IsmailZ.CreeseB.AarslandD.KalesH

It cannot be sold as a dietary supplement (not a legal dietary ingredient)

All treatments are administered by licensed clinicians in a professional setting focused on comfort and safety

The estimated mean change in body weight at week 68 was 20.4% with CagriSema versus 3.0% with placebo (a difference of about 17 percentage points), and more CagriSema participants reached weight-loss thresholds of 5%, 20%, 25%, and 30% than placebo