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Circulation 103 , 113118

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The percentage of patients who responded to treatment increased from 34% to nearly 39% after one year (Rotaru et al., 2020)

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doi: 10.1186/s12916-016-0745-9 39 GeorgakisMKDimitriouNGKaralexiMAMihasCNasothimiouEGTousoulisDet al

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The increase in polarity of the parenteral drug facilitates excretion in the urine

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