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Both in the screening and recalled cohorts, higher caffeine levels were associated with disrupted RBC metabolism, characterized by reduced glycolysis, depletion of adenylate pools or 2,3-bisphosphoglycerate, and increased markers of oxidative stress and osmotic fragility, including kynurenine accumulation

Central to therapeutic development is PGC-1, a master regulator of mitochondrial biogenesis

Discussion SFB are gut commensals found in a range of vertebrate species, but their description remains limited

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In a mouse model of postpartum depression (PPD), GABA levels correlate with specific taxa, including Mucispirillum schaedleri and Bifidobacterium pseudolongum