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All efficacy claims remain preclinical, and combination protocols are entirely anecdotal

Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate

References Milind Umekar, Tanvi Premchandani, Amol Tatode, Mohammad Qutub, Neha Raut, Jayshree Taksande, Ujban Md

The medication works best when combined with dietary modifications and increased physical activity

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