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Withdrawal symptomsSymptoms associated with tobacco addiction withdrawal include a dysphoric or depressed mood, insomnia, irritability, frustration or anger, anxiety, difficulty concentrating, restlessness, decreased heart rate, and increased appetite or weight gain.7 None of the withdrawal symptoms are life-threatening, as they can be with other drugs like alcohol and opiates

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This suggests that nicotine gum and chewing tobacco could have a differential impact on testosterone levels, possibly due to the method of nicotine delivery or the presence of other compounds in the products