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Unlike Rac1 and Cdc42 that can be palmitoylated on their C-terminus to facilitate their recruitment to the lipid raft on the plasma membrane where gamma-secretase was located, RhoA was found mainly in the non-raft fraction (Pianu et al., 2014)

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The PPP also produces ribose-5-phosphate required for ribonucleotide synthesis 12 (Fig

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[20] Another study in aging rats demonstrated extension of life span for rats subjected to constant illumination or to a natural light regimen typical of northern regions