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When energy supply is low, intracellular glutamate leaks outside the cell due to failure of energy-dependent transport mechanisms [19]

It inhibits melanin formation: It functions by inhibiting tyrosinase, an enzyme, which as a result causes inhibition of melanin a pigment that causes dark pigmentation and an uneven skin tone

Increased circulating levels of the vasoconstrictor H 2 O 2 [188, 194] and decreased levels of the vasodilator NO [194, 198] have been noted in preeclampsia and may account for the vasoconstriction and hypertension present in the disease

Unfortunately, there is an experimental limitation to closely investigating the first step of the reaction of OsDHAR