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Aging (Reduced Synthesis Capacity) As you age, production of glutathione declines due to: Reduced activity of gamma-glutamylcysteine ligase (GCL) , the rate-limiting enzyme in glutathione synthesis Decreased cellular energy (ATP) to fuel glutathione recycling Lower levels of precursor amino acids (especially cysteine and glycine) Studies show glutathione levels drop 10-15% per decade after age 40 [3]

doi: 10.1111/pce.12003 10 Clemente-MorenoM

Other skin health benefits include reducing signs of aging, such as wrinkles and fine lines

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To recruit participants, the study coordinator utilized a multifaceted approach, employing fliers, newspaper and radio advertisements, online announcements, and word-of-mouth referrals to reach potential subjects in the local Hershey/Harrisburg, PA area

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