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Elevated blood TMAO levels cause an imbalance in cholesterol homeostasis which leads to influenced macrophages, which in turn causes foam cell development and atherosclerotic plaques [68, 69, 71]

Under oxidative stress conditions, glutathione disulfide (GSSG) and GSH conjugates are exported into the extracellular space for redox homeostasis and detoxification 23

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[DOI] [PubMed] [Google Scholar] 120.Takke A., Shende P

This enzyme plays a role in regulating NAD+ , a molecule essential for cellular energy, metabolic function, and overall cellular health