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Current Neuropharmacology

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After treatment, there were significant improvements in insulin sensitivity, testosterone levels, and markers of inflammation

The copper binds via the histidine imidazole ring, the peptide backbone, and deprotonated amide nitrogens, forming a stable, square-planar coordination complex

Nevertheless, increasing evidence suggests that the relationship of mitochondrial quality control with metal ion-dependent cell death is not simply inhibitory but multifactorial, involving complex interactions in the pathogenesis of various diseases [17]

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