doi: 10.1136/gutjnl-2011-301400
NNMT is overexpressed in select tissues (e.g., adipose tissue, skeletal muscle, etc.) in pathophysiological conditions, making it a clinically relevant target for drug development in several chronic diseases including obesity and diabetes
[82] Vitamin E and its derivatives are particularly attractive therapeutic agents due to their remarkable lack of toxicity in vivo
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We thank the beamline scientists at Diamond Light Source (United Kingdom, proposal MX21625) for their valuable support in structural biology data collection