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May 31, 2024 5 min read 3093 views Hello readers

With respect to insulin responses and metabolism, activation of AKT2 (PKB) and PKC- lead to translocation of GLUT4 containing vesicles to the plasma membrane in adipocytes and skeletal muscle cells resulting in increased glucose uptake in these two tissues

Less muscle means a slower metabolism, reduced insulin sensitivity, and shifts in body composition and strength that heighten the risk for weight gain, fatigue, and bone loss over time