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While LF is generally well-tolerated, some side effects such as temporary fecal loosening have been noted, particularly with oral administration, necessitating careful monitoring during extended use ( 4.3 Probiotics 4.3.1 Definitions, biological functions, and areas of application Probiotics are live microorganisms that offer health benefits
PEG was chosen because it formed the hydrophilic component of a clinically utilized block copolymer (Pluronic, made up of PEG and polypropylene glycol)
The problem is that they get shorter and shorter with chromosome replication and after a while, they cannot protect the DNA strands anymore so DNA gets damaged and our cells cannot do their job